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PAWR 抗体 (C-Term)

This anti-PAWR antibody (ABIN6264442) is a Rabbit Polyclonal antibody detecting PAWR in WB, IHC, ELISA, IF, ICC. Suitable for Human, Mouse, Rat.
产品编号 ABIN6264442
发货至: 中国

Quick Overview for PAWR 抗体 (C-Term) (ABIN6264442)

抗原

See all PAWR 抗体
PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))

适用

  • 33
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人, 小鼠, 大鼠

宿主

  • 33
  • 1

克隆类型

  • 32
  • 2
多克隆

标记

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This PAWR antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    PAR4 Antibody detects endogenous levels of total PAR4.

    预测反应

    Pig,Zebrafish,Rabbit,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human PAR4, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))

    别名

    PAWR

    背景

    Description: Pro-apoptopic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity. Inhibits the transcriptional activation and augments the transcriptional repression mediated by WT1. Down-regulates the anti-apoptotic protein BCL2 via its interaction with WT1. Seems also to be a transcriptional repressor by itself. May be directly involved in regulating the amyloid precursor protein (APP) cleavage activity of BACE1.

    Gene: PAWR

    分子量

    37 kDa

    基因ID

    5074

    UniProt

    Q96IZ0
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