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PASK 抗体 (C-Term)

This anti-PASK antibody is a 兔 多克隆 antibody detecting PASK in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN6264045
发货至: 中国

Quick Overview for PASK 抗体 (C-Term) (ABIN6264045)

抗原

See all PASK 抗体
PASK (PAS Domain Containing Serine/threonine Kinase (PASK))

适用

  • 30
  • 10
  • 9
人, 小鼠

宿主

  • 24
  • 6

克隆类型

  • 25
  • 5
多克隆

标记

  • 19
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PASK antibody is un-conjugated

应用范围

  • 16
  • 9
  • 7
  • 4
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 7
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    PASK Antibody detects endogenous levels of total PASK.

    预测反应

    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human PASK, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    PASK (PAS Domain Containing Serine/threonine Kinase (PASK))

    别名

    PASK

    背景

    Description: Serine/threonine-protein kinase involved in energy homeostasis and protein translation. Phosphorylates EEF1A1, GYS1, PDX1 and RPS6. Probably plays a role under changing environmental conditions (oxygen, glucose, nutrition), rather than under standard conditions. Acts as a sensor involved in energy homeostasis: regulates glycogen synthase synthesis by mediating phosphorylation of GYS1, leading to GYS1 inactivation. May be involved in glucose-stimulated insulin production in pancreas and regulation of glucagon secretion by glucose in alpha cells, however such data require additional evidences. May play a role in regulation of protein translation by phosphorylating EEF1A1, leading to increase translation efficiency. May also participate to respiratory regulation.

    Gene: PASK

    分子量

    142kDa

    基因ID

    23178

    UniProt

    Q96RG2

    途径

    Regulation of Carbohydrate Metabolic Process
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