OSBP 抗体 (Internal Region)
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北京 101111
Quick Overview for OSBP 抗体 (Internal Region) (ABIN6263909)
抗原
See all OSBP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- OSBP Antibody detects endogenous levels of total OSBP.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human OSBP, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Oxysterol Binding Protein (OSBP) (AA 508-807) antibody
OSBP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Oxysterol Binding Protein (OSBP) (AA 324-407) antibodyOSBP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5A3 unconjugated
anti-Oxysterol Binding Protein (OSBP) (AA 700-749) antibodyOSBP 适用: 人, 小鼠, 大鼠, 兔, 犬, Cow, 豚鼠, 马, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Oxysterol Binding Protein (OSBP) (AA 628-802) antibodyOSBP 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Oxysterol Binding Protein (OSBP) (C-Term) antibodyVerified OSBP 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Oxysterol Binding Protein (OSBP) (AA 546-807) antibodyOSBP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- OSBP (Oxysterol Binding Protein (OSBP))
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别名
- OSBP
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背景
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Description: Lipid transporter involved in lipid countertransport between the Golgi complex and membranes of the endoplasmic reticulum: specifically exchanges sterol with phosphatidylinositol 4-phosphate (PI4P), delivering sterol to the Golgi in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum (PubMed:24209621). Binds cholesterol and a range of oxysterols including 25-hydroxycholesterol (PubMed:15746430, PubMed:17428193). Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylates ERK1/2, whereas 25-hydroxycholesterol causes its disassembly (PubMed:15746430). Regulates cholesterol efflux by decreasing ABCA1 stability (PubMed:18450749).
Gene: OSBP
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分子量
- 89 kDa
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基因ID
- 5007
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UniProt
- P22059
抗原
-
