NLRX1 抗体 (Internal Region)
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北京 101111
Quick Overview for NLRX1 抗体 (Internal Region) (ABIN6263660)
抗原
See all NLRX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- NLRX1 Antibody detects endogenous levels of total NLRX1.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human NLRX1, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-NLR Family Member X1 (NLRX1) antibody
NLRX1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-NLR Family Member X1 (NLRX1) (AA 580-630) antibodyNLRX1 适用: 人, 大鼠, 小鼠, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NLR Family Member X1 (NLRX1) (AA 111-210) antibodyNLRX1 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-NLR Family Member X1 (NLRX1) (AA 87-360) antibodyNLRX1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-NLR Family Member X1 (NLRX1) (AA 45-205) antibodyNLRX1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NLR Family Member X1 (NLRX1) (Internal Region) antibodyVerified NLRX1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- NLRX1 (NLR Family Member X1 (NLRX1))
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别名
- NLRX1
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背景
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Description: Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Instead, promotes autophagy by interacting with TUFM and subsequently recruiting the autophagy-related proteins ATG5 and ATG12 (PubMed:22749352). Regulates also MAVS-dependent NLRP3 inflammasome activation to attenuate apoptosis (PubMed:27393910). Has no inhibitory function on NF-kappa-B signaling pathway, but enhances NF-kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (PubMed:18219313).
Gene: NLRX1
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分子量
- 100-110 kDa
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基因ID
- 79671
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UniProt
- Q86UT6
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途径
- SARS-CoV-2 Protein Interactome
抗原
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