NEURL 抗体 (Internal Region)
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北京 101111
Quick Overview for NEURL 抗体 (Internal Region) (ABIN6263606)
抗原
See all NEURL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- Neuralized-1 Antibody detects endogenous levels of total Neuralized-1.
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预测反应
- Pig,Bovine,Rabbit
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human Neuralized-1, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Neuralized Homolog (Drosophila) (NEURL) (pTyr1248) antibody
NEURL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (Internal Region) antibodyNEURL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (Ser357) antibodyNEURL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (Center) antibodyNEURL 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (AA 158-186) antibodyNEURL 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB21920 unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (AA 107-156) antibodyNEURL 适用: 人, 小鼠, 大鼠, 猴, Cow, 犬, 豚鼠, 马, 兔, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (pTyr1112) antibodyNEURL 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (pTyr1221), (pTyr1222) antibodyNEURL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (pTyr877) antibodyNEURL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Neuralized Homolog (Drosophila) (NEURL) (pTyr1221), (pTyr1222) antibodyNEURL 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- NEURL (Neuralized Homolog (Drosophila) (NEURL))
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别名
- NEURL1
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背景
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Description: Plays a role in hippocampal-dependent synaptic plasticity, learning and memory. Involved in the formation of spines and functional synaptic contacts by modulating the translational activity of the cytoplasmic polyadenylation element-binding protein CPEB3. Promotes ubiquitination of CPEB3, and hence induces CPEB3-dependent mRNA translation activation of glutamate receptor GRIA1 and GRIA2. Can function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1 (in vitro), thereby regulating the Notch pathway. Acts as a tumor suppressor, inhibits malignant cell transformation of medulloblastoma (MB) cells by inhibiting the Notch signaling pathway.
Gene: NEURL1
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分子量
- 62kDa
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基因ID
- 9148
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UniProt
- O76050
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途径
- Notch Signaling, EGFR Signaling Pathway
抗原
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