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NEURL 抗体 (Internal Region)

This anti-NEURL antibody is a 兔 多克隆 antibody detecting NEURL in WB, ELISA, IF 和 ICC. Suitable for 人.
产品编号 ABIN6263606
发货至: 中国

Quick Overview for NEURL 抗体 (Internal Region) (ABIN6263606)

抗原

See all NEURL 抗体
NEURL (Neuralized Homolog (Drosophila) (NEURL))

适用

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宿主

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克隆类型

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多克隆

标记

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This NEURL antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    Internal Region

    特异性

    Neuralized-1 Antibody detects endogenous levels of total Neuralized-1.

    预测反应

    Pig,Bovine,Rabbit

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human Neuralized-1, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    NEURL (Neuralized Homolog (Drosophila) (NEURL))

    别名

    NEURL1

    背景

    Description: Plays a role in hippocampal-dependent synaptic plasticity, learning and memory. Involved in the formation of spines and functional synaptic contacts by modulating the translational activity of the cytoplasmic polyadenylation element-binding protein CPEB3. Promotes ubiquitination of CPEB3, and hence induces CPEB3-dependent mRNA translation activation of glutamate receptor GRIA1 and GRIA2. Can function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1 (in vitro), thereby regulating the Notch pathway. Acts as a tumor suppressor, inhibits malignant cell transformation of medulloblastoma (MB) cells by inhibiting the Notch signaling pathway.

    Gene: NEURL1

    分子量

    62kDa

    基因ID

    9148

    UniProt

    O76050

    途径

    Notch Signaling, EGFR Signaling Pathway
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