NEDD8 抗体
Quick Overview for NEDD8 抗体 (ABIN6263583)
抗原
See all NEDD8 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- NEDD8 antibody detects endogenous levels of total NEDD8
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交叉反应
- 人, 猴, 小鼠, 大鼠
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human NEDD8
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亚型
- IgG
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应用备注
- WB: 1:500~1:3000 IHC: 1:50~1:200, IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))
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别名
- NEDD8
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背景
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Description: Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.
Gene: NEDD8
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分子量
- 85kDa
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基因ID
- 4738
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UniProt
- Q15843
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途径
- Ubiquitin Proteasome Pathway
抗原
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