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NEDD8 抗体 (AA 1-32)

NEDD8 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3031967
发货至: 中国
  • 抗原 See all NEDD8 抗体
    NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))
    抗原表位
    • 15
    • 8
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 1-32
    适用
    • 61
    • 29
    • 25
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 58
    • 4
    • 4
    克隆类型
    • 54
    • 12
    多克隆
    标记
    • 30
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NEDD8 antibody is un-conjugated
    应用范围
    • 33
    • 21
    • 21
    • 13
    • 13
    • 13
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    交叉反应 (详细)
    Expected species reactivity: Mouse, Rat, Bovine, Rabbit
    纯化方法
    Purified
    免疫原
    A portion of amino acids 1-32 from the human protein was used as the immunogen for this NEDD8 antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product NEDD8 Primary Antibody
  • 应用备注
    Titration of the NEDD8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the NEDD8 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))
    别名
    NEDD8 (NEDD8 产品)
    别名
    NEDD-8 antibody, Rub1 antibody, CG10679 antibody, Dmel\\CG10679 antibody, NEDD8 antibody, dNEDD8 antibody, nedd8 antibody, ubiquitin antibody, si:zc14a17.5 antibody, GB17785 antibody, DDBDRAFT_0218116 antibody, DDBDRAFT_0238041 antibody, DDB_0218116 antibody, DDB_0238041 antibody, nedd8.S antibody, neural precursor cell expressed, developmentally down-regulated 8 antibody, neural precursor cell expressed, developmentally down-regulated gene 8 antibody, CG10679 gene product from transcript CG10679-RB antibody, Nedd8 antibody, ubiquitin-like protein Nedd8 antibody, neural precursor cell expressed, developmentally down-regulated 8 L homeolog antibody, NEDD8 antibody, Nedd8 antibody, nedd8 antibody, nedd8.L antibody
    背景
    NEDD8 is a ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.
    UniProt
    Q15843
    途径
    Ubiquitin Proteasome Pathway
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