Norrie Disease (Pseudoglioma) 抗体 (Internal Region)
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北京 101111
Quick Overview for Norrie Disease (Pseudoglioma) 抗体 (Internal Region) (ABIN6263552)
抗原
See all Norrie Disease (Pseudoglioma) (NDP) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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原理
- NDP Antibody
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特异性
- NDP Antibody detects endogenous levels of total NDP
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human NDP, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Norrie Disease (Pseudoglioma) (NDP) (AA 25-133) antibody
NDP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Norrie Disease (Pseudoglioma) (NDP) (AA 1-133) antibodyNDP 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Norrie Disease (Pseudoglioma) (NDP) (AA 25-133) antibodyNDP 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Norrie Disease (Pseudoglioma) (NDP) antibodyNDP 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Norrie Disease (Pseudoglioma) (NDP) (Middle Region) antibodyNDP 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Norrie Disease (Pseudoglioma) (NDP) (N-Term) antibodyNDP 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- Norrie Disease (Pseudoglioma) (NDP)
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别名
- NDP
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背景
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Description: Activates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. Plays a central role in retinal vascularization by acting as a ligand for FZD4 that signals via stabilizing beta-catenin (CTNNB1) and activating LEF/TCF-mediated transcriptional programs. Acts in concert with TSPAN12 to activate FZD4 independently of the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1). May be involved in a pathway that regulates neural cell differentiation and proliferation. Possible role in neuroectodermal cell-cell interaction.
Gene: NDP
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分子量
- 15kDa
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基因ID
- 4693
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UniProt
- Q00604
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途径
- Sensory Perception of Sound
抗原
-
