NACA 抗体 (N-Term)
Quick Overview for NACA 抗体 (N-Term) (ABIN6263507)
抗原
See all NACA (NACa1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- NACA Antibody detects endogenous levels of total NACA.
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预测反应
- Pig,Bovine,Sheep,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human NACA, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Nascent Polypeptide Associated Complex alpha 1 (NACa1) (AA 1-215) antibody
NACa1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Nascent Polypeptide Associated Complex alpha 1 (NACa1) (C-Term) antibodyNACa1 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nascent Polypeptide Associated Complex alpha 1 (NACa1) (AA 1-215) antibodyNACa1 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Nascent Polypeptide Associated Complex alpha 1 (NACa1) antibodyNACa1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- NACA (NACa1) (Nascent Polypeptide Associated Complex alpha 1 (NACa1))
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别名
- NACA
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背景
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Description: Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites). May act as a specific coactivator for JUN, binding to DNA and stabilizing the interaction of JUN homodimers with target gene promoters.
Gene: NACA
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分子量
- 24kDa
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基因ID
- 4666
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UniProt
- Q13765
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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