MAD2L2 抗体 (Internal Region)
Quick Overview for MAD2L2 抗体 (Internal Region) (ABIN6263049)
抗原
See all MAD2L2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- MAD2L2 Antibody detects endogenous levels of total MAD2L2.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human MAD2L2, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-MAD2 Mitotic Arrest Deficient-Like 2 (MAD2L2) antibody
MAD2L2 适用: 人 WB, IF, IHC 宿主: 兔 Monoclonal unconjugated
anti-MAD2 Mitotic Arrest Deficient-Like 2 (MAD2L2) (AA 1-211) antibodyMAD2L2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-MAD2 Mitotic Arrest Deficient-Like 2 (MAD2L2) antibodyMAD2L2 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Monoclonal 4D8 unconjugated Recombinant Antibody
anti-MAD2 Mitotic Arrest Deficient-Like 2 (MAD2L2) (AA 198-231), (C-Term) antibodyMAD2L2 适用: 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB48484 unconjugated
anti-MAD2 Mitotic Arrest Deficient-Like 2 (MAD2L2) (AA 1-211) antibodyMAD2L2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-MAD2 Mitotic Arrest Deficient-Like 2 (MAD2L2) (AA 1-211) antibodyMAD2L2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-MAD2 Mitotic Arrest Deficient-Like 2 (MAD2L2) (N-Term) antibodyMAD2L2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- MAD2L2 (MAD2 Mitotic Arrest Deficient-Like 2 (MAD2L2))
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别名
- MAD2L2
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背景
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Description: Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also regulate another aspect of cellular response to DNA damage through regulation of the JNK-mediated phosphorylation and activation of the transcriptional activator ELK1. Inhibits the FZR1- and probably CDC20-mediated activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle. Regulates TCF7L2-mediated gene transcription and may play a role in epithelial-mesenchymal transdifferentiation.
Gene: MAD2L2
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分子量
- 24 kDa
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基因ID
- 10459
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UniProt
- Q9UI95
抗原
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