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Recombinant MAD2L2 抗体

MAD2L2 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Monoclonal 4D8 unconjugated Recombinant Antibody
产品编号 ABIN7127607
发货至: 中国
  • 抗原 See all MAD2L2 抗体
    MAD2L2 (MAD2 Mitotic Arrest Deficient-Like 2 (MAD2L2))
    抗体类型
    Recombinant Antibody
    适用
    • 41
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    宿主
    • 41
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    克隆类型
    • 33
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    单克隆
    标记
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    This MAD2L2 antibody is un-conjugated
    应用范围
    • 31
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    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    Affinity-chromatography
    免疫原
    A synthesized peptide derived from human Mad2L2
    克隆位点
    4D8
    亚型
    IgG
    Top Product
    Discover our top product MAD2L2 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    MAD2L2 (MAD2 Mitotic Arrest Deficient-Like 2 (MAD2L2))
    别名
    MAD2L2 (MAD2L2 产品)
    别名
    mad2b antibody, 2310033C13Rik antibody, MAD2B antibody, REV7 antibody, mad2B antibody, mad2l2-A antibody, xMAD2L2 antibody, POLZ2 antibody, mad2l2 antibody, zgc:110299 antibody, mitotic arrest deficient 2 like 2 antibody, MAD2 mitotic arrest deficient-like 2 antibody, mitotic arrest deficient 2 like 2 S homeolog antibody, MAD2 mitotic arrest deficient-like 2 (yeast) antibody, si:dkey-23c22.2 antibody, mad2l2 antibody, MAD2L2 antibody, Mad2l2 antibody, mad2l2.S antibody, si:dkey-23c22.2 antibody
    背景

    Background: Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also regulate another aspect of cellular response to DNA damage through regulation of the JNK-mediated phosphorylation and activation of the transcriptional activator ELK1. Inhibits the FZR1- and probably CDC20-mediated activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle. Regulates TCF7L2-mediated gene transcription and may play a role in epithelial-mesenchymal transdifferentiation.

    Aliases: Mitotic spindle assembly checkpoint protein MAD2B (Mitotic arrest deficient 2-like protein 2) (MAD2-like protein 2) (REV7 homolog) (hREV7), MAD2L2, MAD2B REV7

    UniProt
    Q9UI95
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