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LC3B 抗体 (N-Term)

Cited in 4+ publications. This anti-LC3B antibody is a 兔 多克隆 antibody detecting LC3B in WB, ELISA, IHC, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6262925
发货至: 中国
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Quick Overview for LC3B 抗体 (N-Term) (ABIN6262925)

抗原

See all LC3B (MAP1LC3B) 抗体
LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This LC3B antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
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    N-Term

    特异性

    LC3A/B Antibody detects endogenous levels of total LC3A/B.

    预测反应

    Pig,Zebrafish,Bovine,Sheep,Dog,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human LC3B, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • Tang, Cui, Luan, Ruan, Wang, Yang, Wang, Liu, Wang: "Human tissue kallikrein 1 ameliorates erectile function via modulation of macroautophagy in aged transgenic rats." in: Andrology, (2018) (PubMed).

    Feng, Lu, He, Wang, Qi, Pi, Zhang: "Mycobacterium smegmatis Induces Neurite Outgrowth and Differentiation in an Autophagy-Independent Manner in PC12 and C17.2 Cells." in: Frontiers in cellular and infection microbiology, Vol. 8, pp. 201, (2018) (PubMed).

    Shao, Yang, Xu, Zhu, Huang, Li, Wu, Yue, Xiong, Chen, Kuang, Fan, Zhu, Zeng: "Inhibition of mTORC1 signaling protects kidney from irradiation-induced toxicity via accelerating recovery of renal stem-like cells." in: Stem cell research & therapy, Vol. 9, Issue 1, pp. 219, (2018) (PubMed).

    Wu, Zheng, Bai, Xia, Zhang, Guo: "HMGB1/RAGE axis mediates the apoptosis, invasion, autophagy, and angiogenesis of the renal cell carcinoma." in: OncoTargets and therapy, Vol. 11, pp. 4501-4510, (2018) (PubMed).

  • 抗原

    LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))

    别名

    MAP1LC3A,MAP1LC3B

    背景

    Description: Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.

    Gene: MAP1LC3B

    分子量

    14.16 kDa

    基因ID

    84557, 81631

    UniProt

    Q9H492, Q9GZQ8

    途径

    Autophagy
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