KNG1 抗体 (N-Term)
Quick Overview for KNG1 抗体 (N-Term) (ABIN6262859)
抗原
See all KNG1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- KNG1 Antibody detects endogenous levels of total KNG1.
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human KNG1, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Kininogen 1 (KNG1) (AA 225-407) antibody
KNG1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 390-644) antibodyKNG1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 214-475) antibodyKNG1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 268-540) antibodyKNG1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 19-380) antibodyKNG1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 148-427) antibodyKNG1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 22-379) antibodyKNG1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 390-644) antibodyKNG1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 1-427) antibodyKNG1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Kininogen 1 (KNG1) (AA 1-427) antibodyKNG1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- KNG1 (Kininogen 1 (KNG1))
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别名
- KNG1
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背景
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Description: 1 Kininogens are inhibitors of thiol proteases, (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII, (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes, (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation and causes (4E1) increase in vascular permeability, (4E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins), (4F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action), (5) LMW-kininogen inhibits the aggregation of thrombocytes, (6) LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting.
Gene: KNG1
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分子量
- 72kDa
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基因ID
- 3827
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UniProt
- P01042
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途径
- ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process
抗原
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