KLHL3 抗体 (N-Term)
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北京 101111
Quick Overview for KLHL3 抗体 (N-Term) (ABIN6262847)
抗原
See all KLHL3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- KLHL3 Antibody detects endogenous levels of total KLHL3.
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预测反应
- Bovine,Horse,Sheep,Rabbit
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human KLHL3, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Kelch-Like 3 (KLHL3) (N-Term) antibody
KLHL3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like 3 (KLHL3) (AA 1-301) antibodyKLHL3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like 3 (KLHL3) (AA 71-120) antibodyKLHL3 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 犬, 兔, 马, Bat, Pig, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like 3 (KLHL3) (AA 51-160) antibodyKLHL3 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like 3 (KLHL3) (AA 1-110) antibodyKLHL3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like 3 (KLHL3) antibodyKLHL3 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like 3 (KLHL3) (AA 1-301) antibodyKLHL3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Kelch-Like 3 (KLHL3) (N-Term) antibodyKLHL3 适用: 人, Cow, 豚鼠, 兔, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like 3 (KLHL3) (C-Term) antibodyKLHL3 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 犬, 马, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like 3 (KLHL3) (AA 10-59) antibodyKLHL3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- KLHL3 (Kelch-Like 3 (KLHL3))
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别名
- KLHL3
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背景
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Description: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron (PubMed:14528312, PubMed:22406640, PubMed:23387299, PubMed:23453970, PubMed:23576762, PubMed:23665031). The BCR(KLHL3) complex acts by mediating ubiquitination of WNK4, an inhibitor of potassium channel KCNJ1, leading to WNK4 degradation (PubMed:23387299, PubMed:23453970, PubMed:23576762, PubMed:23665031). The BCR(KLHL3) complex also mediates ubiquitination and degradation of CLDN8, a tight-junction protein required for paracellular chloride transport in the kidney (By similarity).
Gene: KLHL3
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分子量
- 64 kDa
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基因ID
- 26249
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UniProt
- Q9UH77
抗原
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