FERMT2 抗体 (C-Term)
Quick Overview for FERMT2 抗体 (C-Term) (ABIN6262815)
抗原
See all FERMT2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Kindlin 2 Antibody detects endogenous levels of total Kindlin 2.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human Kindlin 2, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Fermitin Family Member 2 (FERMT2) antibody
FERMT2 适用: 人, 大鼠, 犬, 猴 WB, IHC, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 14A11 unconjugated
anti-Fermitin Family Member 2 (FERMT2) (AA 1-680) antibodyFERMT2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2G11 unconjugated
anti-Fermitin Family Member 2 (FERMT2) (AA 155-232) antibodyFERMT2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fermitin Family Member 2 (FERMT2) (AA 380-550) antibodyFERMT2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fermitin Family Member 2 (FERMT2) (AA 402-451) antibodyFERMT2 适用: 人, Cow, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- FERMT2 (Fermitin Family Member 2 (FERMT2))
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别名
- FERMT2
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背景
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Description: Scaffolding protein that enhances integrin activation mediated by TLN1 and/or TLN2, but activates integrins only weakly by itself. Binds to membranes enriched in phosphoinositides. Enhances integrin-mediated cell adhesion onto the extracellular matrix and cell spreading, this requires both its ability to interact with integrins and with phospholipid membranes. Required for the assembly of focal adhesions. Participates in the connection between extracellular matrix adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits FBLIM1 to focal adhesions. Plays a role in the TGFB1 and integrin signaling pathways. Stabilizes active CTNNB1 and plays a role in the regulation of transcription mediated by CTNNB1 and TCF7L2/TCF4 and in Wnt signaling.
Gene: FERMT2
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分子量
- 78 kDa
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基因ID
- 10979
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UniProt
- Q96AC1
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途径
- Cell-Cell Junction Organization
抗原
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