ILK 抗体 (C-Term)
Quick Overview for ILK 抗体 (C-Term) (ABIN6262572)
抗原
See all ILK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - C-Term
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特异性
 - ILK Antibody detects endogenous levels of total ILK.
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预测反应
 - Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
 - The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
 - A synthesized peptide derived from human ILK, corresponding to a region within C-terminal amino acids.
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亚型
 - IgG
 
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应用备注
 - WB 1:500-1:1000, IHC 1:50-1:100, IF/ICC 1:100-500, ELISA(peptide) 1:20000-1:40000
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限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 1 mg/mL
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缓冲液
 - Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - -20 °C
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储存方法
 - Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
 - 12 months
 
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- ILK (Integrin-Linked Kinase (ILK))
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别名
 - ILK
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背景
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Description: Receptor-proximal protein kinase regulating integrin-mediated signal transduction (PubMed:8538749, PubMed:9736715). May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B (PubMed:8538749, PubMed:9736715).
Gene: ILK
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分子量
 - 59kDa
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基因ID
 - 3611
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UniProt
 - Q13418
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途径
 - Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
 
抗原
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