IFITM3 抗体 (N-Term)
Quick Overview for IFITM3 抗体 (N-Term) (ABIN6262457)
抗原
See all IFITM3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- IFITM3 Antibody detects endogenous levels of total IFITM3.
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预测反应
- Pig,Sheep
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human IFITM3, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-133) antibody
IFITM3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-133) antibodyIFITM3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-30), (N-Term) antibodyIFITM3 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB13975 unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-133) antibodyIFITM3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C8-1B10 unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-133) antibodyIFITM3 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2H4-1D5 unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-57) antibodyIFITM3 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (Internal Region) antibodyVerified IFITM3 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-133) antibodyIFITM3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (N-Term) antibodyIFITM3 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (N-Term) antibodyVerified IFITM3 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- IFITM3 (Interferon-Induced Transmembrane Protein 3 (IFITM3))
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别名
- IFITM3
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背景
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Description: IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV) and Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Plays a critical role in the structural stability and function of vacuolar ATPase (v-ATPase). Establishes physical contact with the v-ATPase of endosomes which is critical for proper clathrin localization and is also required for the function of the v-ATPase to lower the pH in phagocytic endosomes thus establishing an antiviral state.
Gene: IFITM3
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分子量
- 15 kDa
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基因ID
- 10410
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UniProt
- Q01628
抗原
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