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HDAC8 抗体 (N-Term)

The 兔 多克隆 anti-HDAC8 antibody is suitable to detect HDAC8 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC, ELISA, IF 和 ICC.
产品编号 ABIN6262191
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HDAC8 抗体 (N-Term) (ABIN6262191)

抗原

See all HDAC8 抗体
HDAC8 (Histone Deacetylase 8 (HDAC8))

适用

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人, 小鼠, 大鼠

宿主

  • 114
  • 5
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克隆类型

  • 85
  • 35
多克隆

标记

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This HDAC8 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 30
    • 15
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    N-Term

    特异性

    HDAC8 Antibody detects endogenous levels of total HDAC8.

    预测反应

    Pig,Zebrafish,Bovine,Sheep,Rabbit,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human HDAC8, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    HDAC8 (Histone Deacetylase 8 (HDAC8))

    别名

    HDAC8

    背景

    Description: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.

    Gene: HDAC8

    分子量

    42kDa

    基因ID

    55869

    UniProt

    Q9BY41

    途径

    Cellular Glucan Metabolic Process
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