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GZMB 抗体

This anti-GZMB antibody is a 兔 多克隆 antibody detecting GZMB in WB, IHC, ELISA, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6262072
发货至: 中国

Quick Overview for GZMB 抗体 (ABIN6262072)

抗原

See all GZMB 抗体
GZMB (Granzyme B (GZMB))

适用

  • 178
  • 50
  • 25
  • 12
  • 4
  • 4
  • 3
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 95
  • 91
  • 2

克隆类型

  • 102
  • 86
多克隆

标记

  • 101
  • 17
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
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  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GZMB antibody is un-conjugated

应用范围

  • 91
  • 82
  • 43
  • 42
  • 30
  • 24
  • 19
  • 18
  • 14
  • 13
  • 12
  • 10
  • 6
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  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 特异性

    Granzyme B antibody detects endogenous levels of total Granzyme B

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human Granzyme B

    亚型

    IgG
  • 应用备注

    WB: 1:500~1:3000 IHC: 1:50~1:200, IF/ICC 1:100-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C.Stable for 12 months from date of receipt

    有效期

    12 months
  • 抗原

    GZMB (Granzyme B (GZMB))

    别名

    Granzyme B

    背景

    Description: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

    Gene: GZMB

    分子量

    28kDa

    基因ID

    3002

    UniProt

    P10144, P20718

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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