GZMB 抗体
Quick Overview for GZMB 抗体 (ABIN6262072)
抗原
See all GZMB 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Granzyme B antibody detects endogenous levels of total Granzyme B
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human Granzyme B
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亚型
- IgG
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应用备注
- WB: 1:500~1:3000 IHC: 1:50~1:200, IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- GZMB (Granzyme B (GZMB))
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别名
- Granzyme B
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背景
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Description: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Gene: GZMB
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分子量
- 28kDa
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基因ID
- 3002
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UniProt
- P10144, P20718
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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