GEMIN8 抗体 (C-Term)
Quick Overview for GEMIN8 抗体 (C-Term) (ABIN6261938)
抗原
See all GEMIN8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- GEMIN8 Antibody detects endogenous levels of total GEMIN8.
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预测反应
- Pig,Bovine,Horse,Sheep,Dog,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human GEMIN8, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8) (AA 1-242) antibody
GEMIN8 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8) antibodyGEMIN8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))
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别名
- GEMIN8
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背景
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Description: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.
Gene: GEMIN8
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分子量
- 29kDa
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基因ID
- 54960
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UniProt
- Q9NWZ8
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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