FOXP1 抗体 (C-Term)
Quick Overview for FOXP1 抗体 (C-Term) (ABIN6261807)
抗原
See all FOXP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- FOXP1 Antibody detects endogenous levels of total FOXP1.
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预测反应
- Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human FOXP1, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Forkhead Box P1 (FOXP1) (AA 481-677) antibody
FOXP1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 6E4 unconjugated
anti-Forkhead Box P1 (FOXP1) (C-Term) antibodyFOXP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box P1 (FOXP1) (AA 650-677) antibodyFOXP1 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box P1 (FOXP1) (AA 541-677) antibodyFOXP1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box P1 (FOXP1) (AA 1-114) antibodyFOXP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E3-G11 unconjugated
anti-Forkhead Box P1 (FOXP1) (AA 223-270) antibodyFOXP1 适用: 人, 小鼠, 大鼠, 兔, 犬, 马, 猴, 豚鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box P1 (FOXP1) (AA 650-677), (C-Term) antibodyFOXP1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24604 unconjugated
anti-Forkhead Box P1 (FOXP1) (N-Term) antibodyFOXP1 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box P1 (FOXP1) (AA 581-705) antibodyFOXP1 适用: 小鼠, 兔 ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box P1 (FOXP1) (C-Term) antibodyFOXP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- FOXP1 (Forkhead Box P1 (FOXP1))
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别名
- FOXP1
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背景
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Description: Transcriptional repressor (PubMed:18347093, PubMed:26647308). Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential (By similarity). Plays an important role in the specification and differentiation of lung epithelium. Acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program, the function may involve regulation of AGR2. Essential transcriptional regulator of B-cell development. Involved in regulation of cardiac muscle cell proliferation. Involved in the columnar organization of spinal motor neurons. Promotes the formation of the lateral motor neuron column (LMC) and the preganglionic motor column (PGC) and is required for respective appropriate motor axon projections. The segment-appropriate generation of spinal chord motor columns requires cooperation with other Hox proteins. Can regulate PITX3 promoter activity, may promote midbrain identity in embryonic stem cell-derived dopamine neurons by regulating PITX3. Negatively regulates the differentiation of T follicular helper cells T(FH)s. Involved in maintenance of hair follicle stem cell quiescence, the function probably involves regulation of FGF18 (By similarity). Represses transcription of various pro-apoptotic genes and cooperates with NF-kappa B-signaling in promoting B-cell expansion by inhibition of caspase-dependent apoptosis (PubMed:25267198). Binds to CSF1R promoter elements and is involved in regulation of monocyte differentiation and macrophage functions, repression of CSF1R in monocytes seems to involve NCOR2 as corepressor (PubMed:15286807, PubMed:18799727, PubMed:18347093). Involved in endothelial cell proliferation, tube formation and migration indicative for a role in angiogenesis, the role in neovascularization seems to implicate suppression of SEMA5B (PubMed:24023716). Can negatively regulate androgen receptor signaling (PubMed:18640093).
Gene: FOXP1
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分子量
- 75kDa
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基因ID
- 27086
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UniProt
- Q9H334
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途径
- Chromatin Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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