FOXN1 抗体 (N-Term)
Quick Overview for FOXN1 抗体 (N-Term) (ABIN6261798)
抗原
See all FOXN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- FOXN1 Antibody detects endogenous levels of total FOXN1.
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预测反应
- Pig,Bovine,Horse,Rabbit
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human FOXN1, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Forkhead Box N1 (FOXN1) (AA 321-420) antibody
FOXN1 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box N1 (FOXN1) (AA 1-160) antibodyFOXN1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box N1 (FOXN1) (C-Term) antibodyVerified FOXN1 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Forkhead Box N1 (FOXN1) (C-Term) antibodyFOXN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box N1 (FOXN1) (AA 51-100) antibodyFOXN1 适用: 人, 大鼠, 小鼠, 犬, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box N1 (FOXN1) (AA 350-378) antibodyFOXN1 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB32003 unconjugated
anti-Forkhead Box N1 (FOXN1) (AA 357-386), (Middle Region) antibodyFOXN1 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- FOXN1 (Forkhead Box N1 (FOXN1))
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别名
- FOXN1
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背景
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Description: Transcriptional regulator which regulates the development, differentiation, and function of thymic epithelial cells (TECs) both in the prenatal and postnatal thymus. Acts as a master regulator of the TECs lineage development and is required from the onset of differentiation in progenitor TECs in the developing fetus to the final differentiation steps through which TECs mature to acquire their full functionality. Regulates, either directly or indirectly the expression of a variety of genes that mediate diverse aspects of thymus development and function, including MHC Class II, DLL4, CCL25, CTSL, CD40 and PAX1. Regulates the differentiation of the immature TECs into functional cortical TECs (cTECs) and medullary TECs (mTECs). Essential for maintenance of mTECs population in the postnatal thymus. Involved in the morphogenesis and maintenance of the three-dimensional thymic microstructure which is necessary for a fully functional thymus. Plays an important role in the maintenance of hematopoiesis and particularly T lineage progenitors within the bone marrow niche with age. Essential for the vascularization of the thymus anlage. Promotes the terminal differentiation of epithelial cells in the epidermis and hair follicles, partly by negatively regulating the activity of protein kinase C (By similarity). Plays a crucial role in the early prenatal stages of T-cell ontogeny (PubMed:21507891).
Gene: FOXN1
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分子量
- 69kDa
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基因ID
- 8456
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UniProt
- O15353
抗原
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