我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

FGFR2 抗体 (C-Term)

Name: FGFR2 抗体 (C-Term)
SKU: ABIN6261735
Availability: OutOfStock

This anti-FGFR2 antibody is a 兔多克隆 antibody detecting FGFR2 in WB, IHC 和 ELISA. Suitable for 人, 小鼠和大鼠.

Western blot analysis on A549 cell lysate using FGFR2 Antibody,The lane on the left is treated with the antigen-specific peptide. (FGFR2 抗体 (C-Term))

ABIN6266539 at 1/100 staining human kidney tissue sections by IHC-P. (FGFR2 抗体 (C-Term))

IHC

Western blot analysis of extracts from HepG2, using FGFR2 Antibody. (FGFR2 抗体 (C-Term))

3 images

产品编号 ABIN6261735

发货至: 中国

Quick Overview for FGFR2 抗体 (C-Term) (ABIN6261735)

抗原

See all FGFR2 抗体

FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This FGFR2 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Discover our top product FGFR2 Primary Antibody

抗原表位
16

11

10

9

9

8

4

4

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term

特异性

FGFR2 Antibody detects endogenous levels of total FGFR2.

预测反应

Pig,Zebrafish,Bovine,Horse,Rabbit,Dog,Chicken,Xenopus

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human FGFR2, corresponding to a region within C-terminal amino acids.

亚型

IgG
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 1-100) antibody
FGFR2 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated

anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 22-51), (N-Term) antibody
FGFR2 适用: 人, 小鼠 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB01567 unconjugated

anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 621-723) antibody
FGFR2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G3 unconjugated

anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 7-37) antibody
FGFR2 适用: 人, 小鼠, 大鼠, 灵长类 WB, IHC, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated

anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 245-345) antibody
FGFR2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Fibroblast Growth Factor Receptor 2 (FGFR2) antibody
FGFR2 适用: 人 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB17696 unconjugated

anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 21-120) antibody
FGFR2 适用: 人, 小鼠, 大鼠 ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 7-37), (N-Term) antibody
FGFR2 适用: 人 WB, FACS, IF 宿主: 兔 Polyclonal RB15689 unconjugated

anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 794-821) antibody
FGFR2 适用: 人 WB, IHC, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated

anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (Internal Region) antibody
FGFR2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:500-1:3000, IHC: 1:50-1:200, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
抗原

FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

别名

FGFR2

背景

Description: Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. Required for normal embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis and skin development. Plays an essential role in the regulation of osteoblast differentiation, proliferation and apoptosis, and is required for normal skeleton development. Promotes cell proliferation in keratinocytes and immature osteoblasts, but promotes apoptosis in differentiated osteoblasts. Phosphorylates PLCG1, FRS2 and PAK4. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. FGFR2 signaling is down-regulated by ubiquitination, internalization and degradation. Mutations that lead to constitutive kinase activation or impair normal FGFR2 maturation, internalization and degradation lead to aberrant signaling. Over-expressed FGFR2 promotes activation of STAT1.
Gene: FGFR2

分子量

92kDa

基因ID

2263

UniProt

P21802

途径

RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding