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ERO1LB 抗体 (Internal Region)

This anti-ERO1LB antibody is a 兔 多克隆 antibody detecting ERO1LB in WB, IHC, ICC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6261602
发货至: 中国

Quick Overview for ERO1LB 抗体 (Internal Region) (ABIN6261602)

抗原

See all ERO1LB 抗体
ERO1LB (ERO1-Like beta (ERO1LB))

适用

人, 小鼠, 大鼠

宿主

  • 33

克隆类型

  • 33
多克隆

标记

  • 10
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ERO1LB antibody is un-conjugated

应用范围

  • 29
  • 16
  • 13
  • 13
  • 12
  • 9
  • 5
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 7
    • 7
    • 2
    • 1
    • 1
    Internal Region

    特异性

    ERO1LB Antibody detects endogenous levels of total ERO1LB.

    预测反应

    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human ERO1LB, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    ERO1LB (ERO1-Like beta (ERO1LB))

    别名

    ERO1B

    背景

    Description: Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Other protein disulfide isomerase family members can also be reoxidized, but at lower rates compared to P4HB, including PDIA2 (50 % of P4HB reoxidation rate), as well as PDIA3, PDIA4, PDIA6 and NXNDC12 (<10 %). Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. May be involved in oxidative proinsulin folding in pancreatic cells, hence may play a role in glucose homeostasis.

    Gene: ERO1B

    分子量

    40~50 kDa

    基因ID

    56605

    UniProt

    Q86YB8

    途径

    SARS-CoV-2 Protein Interactome
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