ERCC1 抗体 (Internal Region)
Quick Overview for ERCC1 抗体 (Internal Region) (ABIN6261587)
抗原
See all ERCC1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Internal Region
-
特异性
- ERCC1 Antibody detects endogenous levels of total ERCC1.
-
预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Xenopus
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human ERCC1, corresponding to a region within the internal amino acids.
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
-
有效期
- 12 months
-
-
- ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))
-
别名
- ERCC1
-
背景
-
Description: Isoform 1: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.
Gene: ERCC1
-
分子量
- 36kDa
-
基因ID
- 2067
-
UniProt
- P07992
-
途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
-