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Endoglin 抗体 (C-Term)

This 兔多克隆 antibody specifically detects Endoglin in WB, IHC 和 ELISA. It exhibits reactivity toward 人和小鼠.

ABIN6277673 at 1/100 staining Human liver cancer tissue by IHC-P. (Endoglin 抗体 (C-Term))

IHC

2 images

产品编号 ABIN6261533

发货至: 中国

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Quick Overview for Endoglin 抗体 (C-Term) (ABIN6261533)

抗原

See all Endoglin (ENG) 抗体

Endoglin (ENG)

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This Endoglin antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Discover our top product ENG Primary Antibody

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C-Term

特异性

CD105 Antibody detects endogenous levels of total CD105.

预测反应

Pig,Zebrafish,Horse,Sheep,Dog,Chicken

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human CD105, corresponding to a region within C-terminal amino acids.

亚型

IgG
anti-Endoglin (ENG) (AA 58-110) antibody
ENG 适用: 人, 小鼠, 大鼠, 犬 WB, FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Endoglin (ENG) (AA 27-137) antibody
ENG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Endoglin (ENG) (AA 26-136) antibody
ENG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Endoglin (ENG) (AA 26-136) antibody
ENG 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Endoglin (ENG) antibody
ENG 适用: 人 FACS, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 3A9 unconjugated

anti-Endoglin (ENG) (AA 27-226) antibody
ENG 适用: 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Endoglin (ENG) (AA 601-658) antibody
ENG 适用: 人, 大鼠 ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Endoglin (ENG) antibody
ENG 适用: 人, 大鼠 WB, FACS, IP, MS 宿主: 小鼠 Monoclonal MEM-226 unconjugated

anti-Endoglin (ENG) antibody (APC)
ENG 适用: 人, 大鼠 FACS 宿主: 小鼠 Monoclonal MEM-226 APC

anti-Endoglin (ENG) antibody
ENG 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
抗原

Endoglin (ENG)

别名

ENG

背景

Description: Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis (PubMed:21737454, PubMed:23300529). Required for normal structure and integrity of adult vasculature (PubMed:7894484). Regulates the migration of vascular endothelial cells (PubMed:17540773). Required for normal extraembryonic angiogenesis and for embryonic heart development (By similarity). May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors (PubMed:1692830). Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade that ultimately leads to the activation of SMAD transcription factors (PubMed:8370410, PubMed:21737454, PubMed:22347366, PubMed:23300529). Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGFB1 signaling through SMAD3 (PubMed:21737454, PubMed:22347366, PubMed:23300529).
Gene: ENG

分子量

70kDa

基因ID

2022

UniProt

P17813