EEF2K 抗体 (Internal Region)
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北京 101111
Quick Overview for EEF2K 抗体 (Internal Region) (ABIN6261444)
抗原
See all EEF2K 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- EEF2K Antibody detects endogenous levels of total eEF2K.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human eEF2K, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Eukaryotic Elongation Factor-2 Kinase (EEF2K) (N-Term) antibody
EEF2K 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Elongation Factor-2 Kinase (EEF2K) (AA 406-725) antibodyEEF2K 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Elongation Factor-2 Kinase (EEF2K) (AA 1-725) antibodyEEF2K 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Eukaryotic Elongation Factor-2 Kinase (EEF2K) (AA 201-500) antibodyEEF2K 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Elongation Factor-2 Kinase (EEF2K) (Tyr705) antibodyEEF2K 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Elongation Factor-2 Kinase (EEF2K) (AA 331-380), (pSer366) antibodyEEF2K 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Elongation Factor-2 Kinase (EEF2K) (pSer366) antibodyEEF2K 适用: 人, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Elongation Factor-2 Kinase (EEF2K) (AA 337-371), (Ser366) antibodyEEF2K 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal RB56632 unconjugated
anti-Eukaryotic Elongation Factor-2 Kinase (EEF2K) (AA 337-371), (pSer366) antibodyEEF2K 适用: 人 WB 宿主: 兔 Polyclonal RB56631 unconjugated
anti-Eukaryotic Elongation Factor-2 Kinase (EEF2K) (AA 336-385) antibodyEEF2K 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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: "Myostatin inhibits eEF2K-eEF2 by regulating AMPK to suppress protein synthesis." in: Biochemical and biophysical research communications, Vol. 494, Issue 1-2, pp. 278-284, (2017) (PubMed).
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: "Myostatin inhibits eEF2K-eEF2 by regulating AMPK to suppress protein synthesis." in: Biochemical and biophysical research communications, Vol. 494, Issue 1-2, pp. 278-284, (2017) (PubMed).
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- EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))
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别名
- EEF2K
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背景
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Description: Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced.
Gene: EEF2K
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分子量
- 82kDa
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基因ID
- 29904
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UniProt
- O00418
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途径
- AMPK Signaling
抗原
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