EEF2K 抗体 (pSer366)
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北京 101111
Quick Overview for EEF2K 抗体 (pSer366) (ABIN1531227)
抗原
See all EEF2K 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 331-380, pSer366
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原理
- eEF2K (phospho Ser366) Antibody
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特异性
- Phospho-eEF2K (S366) Polyclonal Antibody detects endogenous levels of eEF2K protein only when phosphorylated at S366.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human eEF2K around the phosphorylation site of Ser366. AA range:331-380
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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: "Eukaryotic elongation factor2 kinase controls proliferation and migration of vascular smooth muscle cells." in: Acta physiologica (Oxford, England), (2014) (PubMed).
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- EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))
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别名
- eEF2K
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背景
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Synonyms: EEF2K, Eukaryotic elongation factor 2 kinase, eEF-2 kinase, eEF-2K, Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase
Background: This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq, Jul 2008],
Gene Name: EEF2K
Protein Name: Eukaryotic elongation factor 2 kinase
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分子量
- 82 kDa
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基因ID
- 29904
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OMIM
- 606968
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UniProt
- O00418
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途径
- AMPK Signaling
抗原
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