EEF2K 抗体 (pSer366)
Our Local Distributor
北京 101111
Quick Overview for EEF2K 抗体 (pSer366) (ABIN6255261)
抗原
See all EEF2K 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pSer366
-
原理
- Phospho-eEF2k (Ser366) Antibody
-
特异性
- Phospho-eEF2k (Ser366) Antibody detects endogenous levels of eEF2k.
-
预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
-
纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
-
免疫原
- A synthesized peptide derived from human eEF2k around the phosphorylation site of Ser366.
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
-
有效期
- 12 months
-
-
- EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))
-
别名
- eEF2k
-
背景
-
Description: Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced.
Gene: EEF2K
-
分子量
- 105kDa
-
基因ID
- 29904
-
UniProt
- O00418
-
途径
- AMPK Signaling
抗原
-