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E2F6 抗体 (Internal Region)

This anti-E2F6 antibody is a 兔 多克隆 antibody detecting E2F6 in WB, IHC, ELISA, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN6261413
发货至: 中国

Quick Overview for E2F6 抗体 (Internal Region) (ABIN6261413)

抗原

See all E2F6 抗体
E2F6 (E2F Transcription Factor 6 (E2F6))

适用

  • 33
  • 16
  • 11
  • 6
  • 5
  • 5
  • 5
  • 4
  • 3
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 25
  • 7
  • 1

克隆类型

  • 24
  • 9
多克隆

标记

  • 33
This E2F6 antibody is un-conjugated

应用范围

  • 30
  • 11
  • 10
  • 9
  • 5
  • 5
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region

    特异性

    E2F6 Antibody detects endogenous levels of total E2F6.

    预测反应

    Pig,Bovine,Horse,Sheep,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human E2F6, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • Ai, Zhang, Gao, Qin, Zhong, Gu, Li, Qiao, Tian, Cui, Yang, Bi, Xiao, Chen, Liu, Zhou, Sun, Yang: "Sesquiterpene binding Gly-Leu-Ser/Lys-"co-adaptation pocket" to inhibit lung cancer cell epithelial-mesenchymal transition." in: Oncotarget, Vol. 8, Issue 41, pp. 70192-70203, (2018) (PubMed).

  • 抗原

    E2F6 (E2F Transcription Factor 6 (E2F6))

    别名

    E2F6

    背景

    Description: Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. Overexpression delays the exit of cells from the S-phase.

    Gene: E2F6

    分子量

    31kDa

    基因ID

    1876

    UniProt

    O75461
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