DTNBP1 抗体 (C-Term)
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北京 101111
Quick Overview for DTNBP1 抗体 (C-Term) (ABIN6261377)
抗原
See all DTNBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- DTNBP1 Antibody detects endogenous levels of total DTNBP1.
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预测反应
- Bovine,Horse
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human DTNBP1, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Dystrobrevin Binding Protein 1 (DTNBP1) (AA 258-351) antibody
DTNBP1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Dystrobrevin Binding Protein 1 (DTNBP1) (AA 179-319) antibodyDTNBP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dystrobrevin Binding Protein 1 (DTNBP1) (AA 1-100) antibodyDTNBP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B4 unconjugated
anti-Dystrobrevin Binding Protein 1 (DTNBP1) antibodyDTNBP1 适用: 人 WB, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dystrobrevin Binding Protein 1 (DTNBP1) (AA 110-305) antibodyDTNBP1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dystrobrevin Binding Protein 1 (DTNBP1) antibodyDTNBP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Dystrobrevin Binding Protein 1 (DTNBP1) (AA 101-200) antibodyDTNBP1 适用: 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Dystrobrevin Binding Protein 1 (DTNBP1) antibodyDTNBP1 适用: 人 WB 宿主: 小鼠 Monoclonal 25GB8285 unconjugated
anti-Dystrobrevin Binding Protein 1 (DTNBP1) (AA 8-38), (N-Term) antibodyDTNBP1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB9243 unconjugated
anti-Dystrobrevin Binding Protein 1 (DTNBP1) (AA 296-325), (C-Term) antibodyDTNBP1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB9241 unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))
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别名
- DTNBP1
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背景
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Description: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Associates with the BLOC-2 complex to facilitate the transport of TYRP1 independent of AP-3 function. Plays a role in synaptic vesicle trafficking and in neurotransmitter release. Plays a role in the regulation of cell surface exposure of DRD2. May play a role in actin cytoskeleton reorganization and neurite outgrowth. May modulate MAPK8 phosphorylation. Appears to promote neuronal transmission and viability through regulating the expression of SNAP25 and SYN1, modulating PI3-kinase-Akt signaling and influencing glutamatergic release. Regulates the expression of SYN1 through binding to its promoter. Modulates prefrontal cortical activity via the dopamine/D2 pathway.
Gene: DTNBP1
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分子量
- 39kDa
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基因ID
- 84062
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UniProt
- Q96EV8
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途径
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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