DNMT3B 抗体 (N-Term)
Quick Overview for DNMT3B 抗体 (N-Term) (ABIN6261344)
抗原
See all DNMT3B 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
特异性
- DNMT3B Antibody detects endogenous levels of total DNMT3B.
-
预测反应
- Bovine,Horse,Sheep,Rabbit
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human DNMT3B, corresponding to a region within N-terminal amino acids.
-
亚型
- IgG
-
-
anti-DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) (AA 1-150) antibody
DNMT3B 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 7E5E9C1 unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) (AA 1-150) antibodyDNMT3B 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 4D1A2E5 unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) (N-Term) antibodyDNMT3B 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) (AA 1-100) antibodyDNMT3B 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) (AA 389-417) antibodyDNMT3B 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01906 unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) (AA 389-417) antibodyDNMT3B 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) (AA 1-80) antibodyDNMT3B 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) antibodyDNMT3B 适用: 人 WB, FACS, ICC, DB 宿主: 小鼠 Monoclonal 2280C3a unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) (AA 1-50) antibodyDNMT3B 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) (N-Term) antibodyDNMT3B 适用: 人, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
-
有效期
- 12 months
-
-
- DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))
-
别名
- DNMT3B
-
背景
-
Description: Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as transcriptional co-repressor by associating with CBX4 and independently of DNA methylation. Seems to be involved in gene silencing (By similarity). In association with DNMT1 and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9. Isoforms 4 and 5 are probably not functional due to the deletion of two conserved methyltransferase motifs. Function as transcriptional corepressor by associating with ZHX1. Required for DUX4 silencing in somatic cells (PubMed:27153398).
Gene: DNMT3B
-
分子量
- 97 kDa
-
基因ID
- 1789
-
UniProt
- Q9UBC3
抗原
-
