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TPX2 抗体 (C-Term)

This anti-TPX2 antibody is a 兔 多克隆 antibody detecting TPX2 in WB, ELISA, IHC, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6261299
发货至: 中国

Quick Overview for TPX2 抗体 (C-Term) (ABIN6261299)

抗原

See all TPX2 抗体
TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This TPX2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    C-Term

    特异性

    DIL-2 Antibody detects endogenous levels of total DIL-2.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human DIL-2, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))

    别名

    TPX2

    背景

    Description: Spindle assembly factor required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules (PubMed:18663142, PubMed:19208764). Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation (PubMed:18663142, PubMed:19208764). TPX2 is inactivated upon binding to importin-alpha (PubMed:26165940). At the onset of mitosis, GOLGA2 interacts with importin-alpha, liberating TPX2 from importin-alpha, allowing TPX2 to activates AURKA kinase and stimulates local microtubule nucleation (PubMed:26165940).

    Gene: TPX2

    分子量

    85 kDa

    基因ID

    22974

    UniProt

    Q9ULW0
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