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CLDN10 抗体 (C-Term)

This anti-CLDN10 antibody is a 兔 多克隆 antibody detecting CLDN10 in ELISA, WB, IHC, IF 和 ICC. Suitable for 人 和 小鼠.
产品编号 ABIN6260861
发货至: 中国

Quick Overview for CLDN10 抗体 (C-Term) (ABIN6260861)

抗原

See all CLDN10 抗体
CLDN10 (Claudin 10 (CLDN10))

适用

  • 44
  • 14
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  • 1
  • 1
人, 小鼠

宿主

  • 45
  • 1

克隆类型

  • 46
多克隆

标记

  • 14
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  • 1
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This CLDN10 antibody is un-conjugated

应用范围

  • 15
  • 15
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  • 10
  • 6
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  • 1
ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 17
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    Claudin 10 Antibody detects endogenous levels of total Claudin 10.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human Claudin 10, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    CLDN10 (Claudin 10 (CLDN10))

    别名

    CLDN10

    背景

    Description: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Involved in the regulation of paracellular epithelia permeability to ions in multiple organs. It acts as a paracellular ion channel probably forming permselective pores, isoform 1 appears to create pores preferentially permeable to cations and isoform 2 for anions. In sweat glands and in the thick ascending limb (TAL) of Henle's loop in kidney, it controls paracellular sodium permeability which is essential for proper sweat production and renal function (PubMed:19383724, PubMed:28771254, PubMed:28686597).

    Gene: CLDN10

    分子量

    25kDa

    基因ID

    9071

    UniProt

    P78369

    途径

    Hepatitis C
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