CHD1 抗体 (C-Term)
Quick Overview for CHD1 抗体 (C-Term) (ABIN6260793)
抗原
See all CHD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- CHD1 Antibody detects endogenous levels of total CHD1.
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预测反应
- Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human CHD1, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (C-Term) antibody
CHD1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (AA 1501-1710) antibodyCHD1 适用: 人 ELISA, IHC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (AA 1177-1272) antibodyCHD1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (AA 1177-1272) antibodyCHD1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) antibodyCHD1 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (AA 1331-1380) antibodyCHD1 适用: 人, 小鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 1 (CHD1) (AA 251-467) antibodyCHD1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))
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别名
- CHD1
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背景
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Description: ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. Regulates polymerase II transcription. Also required for efficient transcription by RNA polymerase I, and more specifically the polymerase I transcription termination step. Regulates negatively DNA replication. Not only involved in transcription-related chromatin-remodeling, but also required to maintain a specific chromatin configuration across the genome. Is also associated with histone deacetylase (HDAC) activity (By similarity). Required for the bridging of SNF2, the FACT complex, the PAF complex as well as the U2 snRNP complex to H3K4me3. Functions to modulate the efficiency of pre-mRNA splicing in part through physical bridging of spliceosomal components to H3K4me3 (PubMed:18042460, PubMed:28866611). Required for maintaining open chromatin and pluripotency in embryonic stem cells (By similarity).
Gene: CHD1
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分子量
- 197kDa
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基因ID
- 1105
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UniProt
- O14646
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途径
- Chromatin Binding
抗原
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