CD226 抗体
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北京 101111
Quick Overview for CD226 抗体 (ABIN6260593)
抗原
See all CD226 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- CD226/DNAM-1 antibody detects endogenous levels of total CD226/DNAM-1
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交叉反应
- 人, 小鼠
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human CD226/DNAM-1
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亚型
- IgG
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应用备注
- WB: 1:500~1:3000 IF/ICC: 1:100~1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- CD226
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别名
- CD226/DNAM-1
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背景
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Description: Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell (PubMed:8673704). Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding (PubMed:26755705).
Gene: CD226
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分子量
- 38kDa
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基因ID
- 10666
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UniProt
- Q15762
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
抗原
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