CBP 抗体 (C-Term)
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北京 101111
Quick Overview for CBP 抗体 (C-Term) (ABIN6260516)
抗原
See all CBP (CREBBP) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- CREB-BP Antibody detects endogenous levels of total CREB-BP.
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预测反应
- Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human CREB-BP, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-CREB Binding Protein (CREBBP) (C-Term) antibody
KO Validated CREBBP 适用: 人 WB, IF, IP, ICC, IHC (p), ChIP 宿主: 兔 Polyclonal unconjugated
anti-CREB Binding Protein (CREBBP) (AA 951-1050) antibodyCREBBP 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2H5 unconjugated
anti-CREB Binding Protein (CREBBP) (AA 144-193) antibodyCREBBP 适用: 人, 小鼠, 大鼠, Cow, 犬, 小鸡, 兔, 豚鼠, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CREB Binding Protein (CREBBP) (N-Term) antibodyCREBBP 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CREB Binding Protein (CREBBP) (C-Term) antibodyCREBBP 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CREB Binding Protein (CREBBP) (AA 2217-2442) antibodyCREBBP 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CREB Binding Protein (CREBBP) antibodyCREBBP 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CREB Binding Protein (CREBBP) antibodyCREBBP 适用: 人 WB, IP, ICC, DB 宿主: 小鼠 Monoclonal CBP5I001 unconjugated
anti-CREB Binding Protein (CREBBP) (Ser262) antibodyCREBBP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CREB Binding Protein (CREBBP) (AA 2100-2200) antibody (Atto 390)CREBBP 适用: 人 WB, IHC 宿主: 兔 Polyclonal Atto 390
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- CBP (CREBBP) (CREB Binding Protein (CREBBP))
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别名
- CREBBP
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背景
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Description: Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Acetylates PCNA, acetylation promotes removal of chromatin-bound PCNA and its degradation during nucleotide excision repair (NER) (PubMed:24939902).
Gene: CREBBP
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分子量
- 265kDa
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基因ID
- 1387
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UniProt
- Q92793
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途径
- TCR Signaling, Interferon-gamma Pathway, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
抗原
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