Casein Kinase 1 gamma 2 抗体 (C-Term)
Quick Overview for Casein Kinase 1 gamma 2 抗体 (C-Term) (ABIN6260467)
抗原
See all Casein Kinase 1 gamma 2 (CSNK1G2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Casein Kinase Igamma2 Antibody detects endogenous levels of total Casein Kinase Igamma2.
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预测反应
- Pig,Bovine,Sheep,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human Casein Kinase Igamma2, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Casein Kinase 1, gamma 2 (CSNK1G2) (AA 316-415), (Isoform gamma 2) antibody
CSNK1G2 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, gamma 2 (CSNK1G2) (AA 315-415) antibodyCSNK1G2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F5 unconjugated
anti-Casein Kinase 1, gamma 2 (CSNK1G2) (AA 1-415) antibodyCSNK1G2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E6 unconjugated
anti-Casein Kinase 1, gamma 2 (CSNK1G2) (AA 1-415) antibodyCSNK1G2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, gamma 2 (CSNK1G2) (AA 1-415) antibodyCSNK1G2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F4 unconjugated
anti-Casein Kinase 1, gamma 2 (CSNK1G2) antibodyCSNK1G2 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, gamma 2 (CSNK1G2) (N-Term) antibodyCSNK1G2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, gamma 2 (CSNK1G2) (AA 130-179) antibodyCSNK1G2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, gamma 2 (CSNK1G2) (AA 170-415) antibodyCSNK1G2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, gamma 2 (CSNK1G2) (N-Term) antibodyCSNK1G2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- Casein Kinase 1 gamma 2 (CSNK1G2) (Casein Kinase 1, gamma 2 (CSNK1G2))
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别名
- CSNK1G2
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背景
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Description: Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3. Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses. Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis. Triggers PER1 proteasomal degradation probably through phosphorylation.
Gene: CSNK1G2
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分子量
- 47kDa
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基因ID
- 1455
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UniProt
- P78368
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途径
- Hedgehog Signaling
抗原
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