CALCOCO2 抗体 (Internal Region)
Quick Overview for CALCOCO2 抗体 (Internal Region) (ABIN6260408)
抗原
See all CALCOCO2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- CALCOCO2 Antibody detects endogenous levels of total CALCOCO2.
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human CALCOCO2, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) (AA 137-446) antibody
CALCOCO2 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) (AA 347-446) antibodyCALCOCO2 适用: 人 WB, IF, ELISA 宿主: 小鼠 Monoclonal 2A11 unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) antibodyCALCOCO2 适用: 人, 大鼠, 猴, 犬 WB, IF, FACS 宿主: 小鼠 Monoclonal 2D11 unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) (AA 1-446) antibodyCALCOCO2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) (AA 347-446) antibodyCALCOCO2 适用: 人 WB, IF, ELISA 宿主: 小鼠 Monoclonal 3C4 unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) (AA 1-446) antibodyCALCOCO2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) (AA 137-446) antibodyCALCOCO2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) antibodyCALCOCO2 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- CALCOCO2 (Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2))
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别名
- CALCOCO2
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背景
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Description: Xenophagy-specific receptor required for autophagy-mediated intracellular bacteria degradation. Acts as an effector protein of galectin-sensed membrane damage that restricts the proliferation of infecting pathogens such as Salmonella typhimurium upon entry into the cytosol by targeting LGALS8-associated bacteria for autophagy (PubMed:22246324). Initially orchestrates bacteria targeting to autophagosomes and subsequently ensures pathogen degradation by regulating pathogen-containing autophagosome maturation (PubMed:23022382, PubMed:25771791). Bacteria targeting to autophagosomes relies on its interaction with MAP1LC3A, MAP1LC3B and/or GABARAPL2, whereas regulation of pathogen-containing autophagosome maturation requires the interaction with MAP3LC3C (PubMed:23022382, PubMed:25771791). May play a role in ruffle formation and actin cytoskeleton organization and seems to negatively regulate constitutive secretion (PubMed:17635994).
Gene: CALCOCO2
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分子量
- 52 kDa
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基因ID
- 10241
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UniProt
- Q13137
抗原
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