BBS7 抗体 (Internal Region)
Quick Overview for BBS7 抗体 (Internal Region) (ABIN6260213)
抗原
See all BBS7 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Internal Region
-
特异性
- BBS7 Antibody detects endogenous levels of total BBS7.
-
预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human BBS7, corresponding to a region within the internal amino acids.
-
亚型
- IgG
-
-
anti-Bardet-Biedl Syndrome 7 (BBS7) (AA 1-715) antibody
BBS7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 7 (BBS7) (Internal Region) antibodyVerified BBS7 适用: 人, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 7 (BBS7) (AA 574-672) antibodyBBS7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H6 unconjugated
anti-Bardet-Biedl Syndrome 7 (BBS7) antibodyBBS7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 7 (BBS7) (AA 289-393) antibodyBBS7 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 7 (BBS7) (AA 1-715) antibodyBBS7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Bardet-Biedl Syndrome 7 (BBS7) (AA 1-270) antibodyBBS7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
-
有效期
- 12 months
-
-
- BBS7 (Bardet-Biedl Syndrome 7 (BBS7))
-
别名
- BBS7
-
背景
-
Description: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization.
Gene: BBS7
-
分子量
- 75 kDa
-
基因ID
- 55212
-
UniProt
- Q8IWZ6
-
途径
- Hedgehog Signaling
抗原
-
