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ATG4A 抗体 (N-Term)

This anti-ATG4A antibody is a 兔 多克隆 antibody detecting ATG4A in WB, ELISA, IF 和 ICC. Suitable for 人 和 小鼠.
产品编号 ABIN6260104
发货至: 中国

Quick Overview for ATG4A 抗体 (N-Term) (ABIN6260104)

抗原

See all ATG4A 抗体
ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This ATG4A antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    N-Term

    特异性

    ATG4A Antibody detects endogenous levels of total ATG4A.

    预测反应

    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human ATG4A, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))

    别名

    ATG4A

    背景

    Description: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Has also an activity of delipidating enzyme for the PE-conjugated forms.

    Gene: ATG4A

    分子量

    45 kDa

    基因ID

    115201

    UniProt

    Q8WYN0

    途径

    Autophagy
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