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ATG4A 抗体 (N-Term)

ATG4A 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260104
发货至: 中国
  • 抗原 See all ATG4A 抗体
    ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
    抗原表位
    • 14
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 51
    • 31
    • 26
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    人, 小鼠
    宿主
    • 44
    • 4
    • 2
    • 1
    克隆类型
    • 45
    • 6
    多克隆
    标记
    • 28
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATG4A antibody is un-conjugated
    应用范围
    • 23
    • 22
    • 13
    • 12
    • 11
    • 7
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    ATG4A Antibody detects endogenous levels of total ATG4A.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human ATG4A, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product ATG4A Primary Antibody
  • 应用备注
    WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
    别名
    ATG4A (ATG4A 产品)
    背景

    Description: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Has also an activity of delipidating enzyme for the PE-conjugated forms.

    Gene: ATG4A

    分子量
    45 kDa
    基因ID
    115201
    UniProt
    Q8WYN0
    途径
    Autophagy
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