APOBEC3C 抗体
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北京 101111
Quick Overview for APOBEC3C 抗体 (ABIN6259986)
抗原
See all APOBEC3C 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- APOBEC3C Antibody detects endogenous levels of total APOBEC3C
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交叉反应
- 人, 小鼠
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human APOBEC3C
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亚型
- IgG
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anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3C (APOBEC3C) (Center) antibody
APOBEC3C 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3C (APOBEC3C) (AA 1-190) antibodyAPOBEC3C 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3C (APOBEC3C) (AA 1-190) antibodyAPOBEC3C 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3C (APOBEC3C) (AA 1-190) antibodyAPOBEC3C 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3C (APOBEC3C) (C-Term) antibodyVerified APOBEC3C 适用: 人 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3C (APOBEC3C) (AA 1-190) antibodyAPOBEC3C 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3C (APOBEC3C) (AA 91-190) antibodyAPOBEC3C 适用: 人 ELISA, IP 宿主: 小鼠 Monoclonal 3E6 unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3C (APOBEC3C) (AA 143-177) antibodyAPOBEC3C 适用: 人 WB 宿主: 兔 Polyclonal RB56223 unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3C (APOBEC3C) (AA 1-190) antibodyAPOBEC3C 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000 IHC 1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- APOBEC3C (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3C (APOBEC3C))
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别名
- APOBEC3C
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背景
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Description: DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. Exhibits antiviral activity against simian immunodeficiency virus (SIV), hepatitis B virus (HBV), herpes simplex virus 1 (HHV-1) and Epstein-Barr virus (EBV) and may inhibit the mobility of LTR and non-LTR retrotransposons. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
Gene: APOBEC3C
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分子量
- 23 kDa
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基因ID
- 27350
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UniProt
- Q9NRW3
抗原
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