AKR1C4 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for AKR1C4 抗体 (N-Term) (ABIN6259863)
抗原
See all AKR1C4 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
原理
- AKR1C4 Antibody
-
特异性
- AKR1C4 Antibody detects endogenous levels of total AKR1C4
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human AKR1C4, corresponding to a region within N-terminal amino acids.
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:1000-3000, IHC 1:50-1:200 IF/ICC 1:100-1:500
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
-
有效期
- 12 months
-
-
- AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))
-
别名
- AKR1C4
-
背景
-
Description: Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.
Gene: AKR1C4
-
分子量
- 37 kDa
-
基因ID
- 1109
-
UniProt
- P17516
-
途径
- Steroid Hormone Biosynthesis
抗原
-