Acylglycerol Kinase 抗体 (C-Term)
Quick Overview for Acylglycerol Kinase 抗体 (C-Term) (ABIN6259823)
抗原
See all Acylglycerol Kinase (AGK) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- AGK Antibody detects endogenous levels of total AGK.
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预测反应
- Bovine,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human AGK, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Acylglycerol Kinase (AGK) (AA 32-65) antibody
AGK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Acylglycerol Kinase (AGK) (AA 35-84) antibodyAGK 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 兔, Cow, 马, Hamster, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Acylglycerol Kinase (AGK) (AA 15-300) antibodyAGK 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Acylglycerol Kinase (AGK) (AA 335-422) antibodyAGK 适用: 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Acylglycerol Kinase (AGK) (C-Term) antibodyVerified AGK 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Acylglycerol Kinase (AGK) antibodyAGK 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Acylglycerol Kinase (AGK) (AA 1-422) antibodyAGK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Acylglycerol Kinase (AGK) (AA 107-156) antibodyAGK 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 兔, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Acylglycerol Kinase (AGK) (AA 233-422) antibodyAGK 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Acylglycerol Kinase (AGK) (AA 1-422) antibodyAGK 适用: 人 WB 宿主: 小鼠 Monoclonal unconjugated
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应用备注
- WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- Acylglycerol Kinase (AGK)
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别名
- AGK
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背景
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Description: Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively (PubMed:15939762). Does not phosphorylate sphingosine (PubMed:15939762). Independently of its lipid kinase activity, acts as a component of the TIM22 complex (PubMed:28712724, PubMed:28712726). The TIM22 complex mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane by forming a twin-pore translocase that uses the membrane potential as the external driving force (PubMed:28712724, PubMed:28712726). In the TIM22 complex, required for the import of a subset of metabolite carriers into mitochtondria, such as ANT1/SLC25A4 and SLC25A24, while it is not required for the import of TIMM23 (PubMed:28712724). Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth (PubMed:15939762).
Gene: AGK
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分子量
- 47 kDa
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基因ID
- 55750
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UniProt
- Q53H12
抗原
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