ABCA4 抗体 (C-Term)
Quick Overview for ABCA4 抗体 (C-Term) (ABIN6259677)
抗原
See all ABCA4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- ABCA4 Antibody detects endogenous levels of total ABCA4.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human ABCA4, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4) (AA 2250-2263) antibody
Verified ABCA4 适用: 人, 小鼠 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4) (AA 1398-1727) antibodyABCA4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4) antibodyABCA4 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4) (AA 2174-2273) antibodyABCA4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4) antibodyABCA4 适用: Cow WB, IHC 宿主: 小鼠 Monoclonal 3F4 unconjugated
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应用备注
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- ABCA4 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4))
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别名
- ABCA4
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背景
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Description: In the visual cycle, acts as an inward-directed retinoid flipase, retinoid substrates imported by ABCA4 from the extracellular or intradiscal (rod) membrane surfaces to the cytoplasmic membrane surface are all-trans-retinaldehyde (ATR) and N-retinyl-phosphatidyl-ethanolamine (NR-PE). Once transported to the cytoplasmic surface, ATR is reduced to vitamin A by trans-retinol dehydrogenase (tRDH) and then transferred to the retinal pigment epithelium (RPE) where it is converted to 11-cis-retinal. May play a role in photoresponse, removing ATR/NR-PE from the extracellular photoreceptor surfaces during bleach recovery.
Gene: ABCA4
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分子量
- 256 kDa
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基因ID
- 24
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UniProt
- P78363
抗原
-
