Serotonin Receptor 1A 抗体 (Internal Region)
(1 reference)Quick Overview for Serotonin Receptor 1A 抗体 (Internal Region) (ABIN6259651)
抗原
See all Serotonin Receptor 1A (HTR1A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- 5HT1A Receptor Antibody detects endogenous levels of total 5HT1A Receptor.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human 5HT1A Receptor, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Serotonin Receptor 1A (HTR1A) antibody
HTR1A 适用: 人 WB, IF, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 1A (HTR1A) (AA 301-400) antibodyHTR1A 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 1A (HTR1A) (N-Term) antibodyHTR1A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 1A (HTR1A) antibodyMicroarray verified HTR1A 适用: 人 IHC 宿主: 小鼠 Monoclonal MAB765230 unconjugated
anti-Serotonin Receptor 1A (HTR1A) antibodyMicroarray verified HTR1A 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB759700 unconjugated
anti-Serotonin Receptor 1A (HTR1A) (AA 230-334) antibodyHTR1A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 1A (HTR1A) (AA 239-273) antibodyHTR1A 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB46792 unconjugated
anti-Serotonin Receptor 1A (HTR1A) (N-Term) antibodyHTR1A 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 1A (HTR1A) antibodyMicroarray verified HTR1A 适用: 人 IHC 宿主: 小鼠 Monoclonal MAB289500 unconjugated
anti-Serotonin Receptor 1A (HTR1A) antibodyHTR1A 适用: 人, 大鼠 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 19A9-2 unconjugated
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应用备注
- WB 1:500-1:2000, IHC-p 1:50-1:200, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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: "Role of 5-HT1A receptor in insular cortex mediating stress - induced visceral sensory dysfunction." in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, Vol. 28, Issue 7, pp. 1104-13, (2018) (PubMed).
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: "Role of 5-HT1A receptor in insular cortex mediating stress - induced visceral sensory dysfunction." in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, Vol. 28, Issue 7, pp. 1104-13, (2018) (PubMed).
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- Serotonin Receptor 1A (HTR1A)
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别名
- HTR1A
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背景
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Description: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca2+ ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.
Gene: HTR1A
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分子量
- 46 kDa
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基因ID
- 3350
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UniProt
- P08908
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途径
- JAK/STAT Signaling, Synaptic Membrane, Feeding Behaviour
抗原
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