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NSG1 抗体 (Internal Region)

This anti-NSG1 antibody is a 兔 多克隆 antibody detecting NSG1 in WB, ELISA, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6259604
发货至: 中国

Quick Overview for NSG1 抗体 (Internal Region) (ABIN6259604)

抗原

See all NSG1 (D4S234E) 抗体
NSG1 (D4S234E) (Neuron-Specific Protein Family Member 1 (D4S234E))

适用

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人, 小鼠, 大鼠

宿主

  • 37
  • 3
  • 1

克隆类型

  • 38
  • 3
多克隆

标记

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This NSG1 antibody is un-conjugated

应用范围

  • 41
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  • 13
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  • 3
  • 3
  • 1
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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 15
    • 8
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    • 1
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    Internal Region

    特异性

    NSG1 Antibody detects endogenous levels of total NSG1.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human NSG1, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    NSG1 (D4S234E) (Neuron-Specific Protein Family Member 1 (D4S234E))

    别名

    NSG1

    背景

    Description: Plays a role in the recycling mechanism in neurons of multiple receptors, including AMPAR, APP and L1CAM and acts at the level of early endosomes to promote sorting of receptors toward a recycling pathway. Regulates sorting and recycling of GRIA2 through interaction with GRIP1 and then contributes to the regulation of synaptic transmission and plasticity by affecting the recycling and targeting of AMPA receptors to the synapse (By similarity). Is required for faithful sorting of L1CAM to axons by facilitating trafficking from somatodendritic early endosome or the recycling endosome (By similarity). In an other hand, induces apoptosis via the activation of CASP3 in response to DNA damage (PubMed:20599942, PubMed:20878061).

    Gene: NSG1

    分子量

    26 kDa

    基因ID

    27065

    UniProt

    P42857
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