NSG1 抗体 (AA 1-100)
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- 抗原 See all NSG1 (D4S234E) 抗体
- NSG1 (D4S234E) (Neuron-Specific Protein Family Member 1 (D4S234E))
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抗原表位
- AA 1-100
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适用
- 小鼠, 猴
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NSG1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 猴, 小鼠
- 预测反应
- Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human NEEP21
- 亚型
- IgG
- Top Product
- Discover our top product D4S234E Primary Antibody
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anti-Neuron-Specific Protein Family Member 1 (D4S234E) (AA 1-185) antibody
D4S234E 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C3 unconjugated
anti-Neuron-Specific Protein Family Member 1 (D4S234E) (AA 1-185) antibodyD4S234E 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1D22 unconjugated
anti-Neuron-Specific Protein Family Member 1 (D4S234E) (N-Term) antibodyVerified D4S234E 适用: 小鼠, 大鼠 WB, ELISA, ICC 宿主: 山羊 Polyclonal unconjugated
anti-Neuron-Specific Protein Family Member 1 (D4S234E) (Internal Region) antibodyD4S234E 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neuron-Specific Protein Family Member 1 (D4S234E) (Internal Region) antibodyD4S234E 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neuron-Specific Protein Family Member 1 (D4S234E) (Internal Region) antibodyD4S234E 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neuron-Specific Protein Family Member 1 (D4S234E) (N-Term) antibodyD4S234E 适用: 人, 小鼠, 大鼠, 猴, Cow, 豚鼠, Hamster, 小鸡, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Neuron-Specific Protein Family Member 1 (D4S234E) (AA 1-80) antibodyD4S234E 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Neuron-Specific Protein Family Member 1 (D4S234E) (N-Term) antibodyD4S234E 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- NSG1 (D4S234E) (Neuron-Specific Protein Family Member 1 (D4S234E))
- 别名
- Neep21 (D4S234E 产品)
- 别名
- D4S234 antibody, D4S234E antibody, NEEP21 antibody, P21 antibody, Neep21 antibody, m234 antibody, p21 antibody, Bsmrb antibody, PEP1 antibody, neuronal vesicle trafficking associated 1 antibody, neuron specific gene family member 1 antibody, NSG1 antibody, Nsg1 antibody
- 背景
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Synonyms: neuron-enriched endosomal 21 kDa protein, NSG1_HUMAN.
Background: NEEP21, also known as Brain neuron cytoplasmic protein 1, NSG1 (neuron-specific proteins family member 1), P21 or D4S234E, is a single pass type II membrane protein belonging to the NSG family. It is highly expressed during neuronal maturation but its expression is downregulated in adult tissues. NEEP21 predominantly localizes to Rab 4-positive early endosomes in the somatodendritic neuronal compartment and is essential for proper receptor sorting and recycling in neurons. It associates with GRIP1 and GluR-2 and mediates the surface expression of GluR-2. When this interaction is interrupted, GluR-2 accumulates in early endosomes and leads to changes in evoked synaptic current properties. In addition, NEEP21 forms a complex with the SNARE protein, Syntaxin 13 (also known as Syntaxin 12), and participates in the recycling of transferrin receptors (TFRs) and NTR2 (neurotensin receptor 2).
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