SMUG1 抗体 (Internal Region)
Quick Overview for SMUG1 抗体 (Internal Region) (ABIN6259193)
抗原
See all SMUG1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- SMUG1 Antibody detects endogenous levels of total SMUG1.
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预测反应
- Pig,Bovine,Horse,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human SMUG1, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1) (N-Term) antibody
Verified SMUG1 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1) (AA 1-177) antibodySMUG1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D5 unconjugated
anti-Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1) (AA 2-78) antibodySMUG1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1) (AA 1-270) antibodySMUG1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1) antibodySMUG1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1) (AA 1-177) antibodySMUG1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1) (AA 110-159) antibodySMUG1 适用: 人, 小鼠, 大鼠, 猴, 马, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1) (AA 1-270) antibodySMUG1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1) (Center) antibodySMUG1 适用: 人, 小鼠, 大鼠, 猴 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- SMUG1 (Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1))
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别名
- SMUG1
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背景
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Description: Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The activity is greater toward mismatches (U/G) compared to matches (U/A). Excises uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA, but not analogous cytosine derivatives (5-hydroxycytosine and 5-formylcytosine), nor other oxidized bases. The activity is damage-specific and salt-dependent. The substrate preference is the following: ssDNA > dsDNA (G pair) = dsDNA (A pair) at low salt concentration, and dsDNA (G pair) > dsDNA (A pair) > ssDNA at high salt concentration.
Gene: SMUG1
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分子量
- 32 kDa
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基因ID
- 23583
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UniProt
- Q53HV7
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途径
- DNA Damage Repair
抗原
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