RAD51 Homolog B 抗体
Quick Overview for RAD51 Homolog B 抗体 (ABIN6259179)
抗原
See all RAD51 Homolog B (Rad51B) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- RAD51L1 Antibody detects endogenous levels of total RAD51L1
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交叉反应
- 人, 猴, 小鼠
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide
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亚型
- IgG
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anti-RAD51 Homolog B (Rad51B) (Middle Region) antibody
Rad51B 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-RAD51 Homolog B (Rad51B) (AA 143-192) antibodyRad51B 适用: 人, 猴, 犬, 豚鼠, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAD51 Homolog B (Rad51B) (AA 1-384) antibodyRad51B 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-RAD51 Homolog B (Rad51B) (AA 251-300) antibodyRad51B 适用: 人, 小鼠, 猴, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-RAD51 Homolog B (Rad51B) (AA 1-384) antibodyRad51B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAD51 Homolog B (Rad51B) (Center) antibodyRad51B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAD51 Homolog B (Rad51B) (AA 201-250) antibodyRad51B 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500~1:1000 IHC: 1:50~1:200, IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- RAD51 Homolog B (Rad51B)
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别名
- RAD51L1
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背景
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Description: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. May promote the assembly of presynaptic RAD51 nucleoprotein filaments. Binds single-stranded DNA and double-stranded DNA and has DNA-dependent ATPase activity. Part of the RAD21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. The BCDX2 subcomplex RAD51B:RAD51C exhibits single-stranded DNA-dependent ATPase activity suggesting an involvement in early stages of the HR pathway.
Gene: RAD51B
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分子量
- 45 kDa
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基因ID
- 5890
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UniProt
- O15315
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途径
- DNA Damage Repair
抗原
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